Radiological Protection in Therapy with Radiopharmaceuticals
Radiopharmaceuticals are increasingly used for the treatment of various cancers with novel radionuclides, compounds, tracer molecules, and administration techniques. The goal of radiation therapy, including therapy with radiopharmaceuticals, is to optimise the relationship between tumour control probability and potential complications in normal organs and tissues. This report provides an overview of therapy procedures and a framework for calculating radiation doses for various treatment approaches.
Provides a step-by-step guide to implementing external beam treatment plans that meet clinical requirements for each major disease site. The book focuses on the technical aspects of treatment planning and the major challenges in creating highly conformal dose distributions, referenced to as treatment plans, for external beam radiotherapy.
A comprehensive guide for the practicing physician and medical physicist in the management of intracranial and extracranial disease. It is a state-of-the-science book presenting the scientific principles, clinical background and procedures, treatment planning, and treatment delivery of SRS and SBRT for the treatment of tumours throughout the body.
Tests and reinforces your knowledge of key concepts, critical studies, and major clinical guidelines, with the most important radiation oncology citations included. Detailed questions cover natural history, epidemiology, diagnosis, staging, treatment options, and treatment-related side effects all in a newly configured format.
Provides the essential biostatistical concepts, oncology-specific examples, and applicable problem sets for medical oncologists, radiation oncologists, and surgical oncologists. All examples are relevant to oncology and demonstrate how to apply core conceptual knowledge and methods related to hypothesis testing, correlation and regression, ......
The only text to integrate the basics of radiology, characteristics and differences of testing modalities, and interpretation skills This unique book fills a void in radiology interpretation texts by encompassing the foundational tools and concepts of the full range of medical imaging, including radiology, the basics of interpretation of plain ......
Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection
This report provides a review of stem cells/progenitor cells and their responses to ionising radiation in relation to issues relevant to stochastic effects of radiation which form a major part of the ICRP system of radiological protection. Current information on stem cell characteristics, maintenance and renewal, evolution with age, location in stem cell "niches", radiosensitivity to acute and protracted exposures, is presented in a series of substantial reviews as Annexes concerning haematopoietic tissue, mammary gland, thyroid, digestive tract, lung, skin and bone. This foundation of knowledge of stem cells is used in the main text of the report to provide a biological insight to issues such as the linear-no-threshold (LNT) model, cancer risk among tissues, dose-rate effects and changes in the risk of radiation carcinogenesis by age at exposure and attained age.
Radiation Dose to Patients from Radiopharmaceuticals: a Compendium of Current Information Related to Frequently Used Substances
This report provides a compendium of current information relating to radiation dose to patients, including biokinetic models, biokinetic data, dose coefficients for organ and tissue absorbed doses, and effective dose for major radiopharmaceuticals based on ICRP radiation protection guidance. These data were compiled from ICRP Publications 53, 80, and 106 and related amendments and corrections. This report also includes new information for 82Rb-chloride, iodide (123I, 124I, 125I, and 131I) and 123I labelled 2ss-carbomethoxy 3ss-(4-iodophenyl)-N-(3-fluoropropyl) nortropane (FPCIT). The data presented in this report are intended for diagnostic nuclear medicine and not for therapeutic applications.
