As one of the first oncogenes identified, Myc has enjoyed an illustrious history. In reflection of 30 years of research and in excess of 20,000 published articles, two major themes emerge. First, the fine-tuned regulation and numerous activities of Myc in normal cells are unparalleled and a beauty to behold. Second, when this regulation is lost, Myc rears its beastly head and takes the role of one of the most prominent and intriguing of oncoproteins. (From Myc: The Beauty and the Beast by Amanda R. Wasylishen and Linda Z. Penn in Genes & Cancer Vol 1 No 6, 2010.) MYC-A Far-Reaching Cancer Gene edited by Dr. Chi Van Dang at Johns Hopkins is a truly outstanding compilation of comprehensive reviews ("Monographs") that addresses the myriad roles of this very important oncogene in growth, development, metabolism, and cancer. As Dr. Dang states in his introductory remarks, "This special issue captures the excitement that is associated with MYC-mediated tumorigenesis through reviews that span a timeline of MYC research including a fundamental understanding of how the MYC gene itself is regulated, the study of Myc in model organisms, Myc function, and target genes to translational research in search of new therapeutic modalities for the treatment of cancer."
Chronic pain. Insomnia. Depression. These are just a few of the ongoing, debilitating symptoms that plague some breast-cancer survivors long after their treatments have officially ended. This book is filled with portraits of more than seventy women who are living with the aftermath of breast cancer.
Authored by some of the world's leading Cancer experts from wide ranging disciplines including oncology, radiation oncology, neurosurgery, orthopaedic surgery and radiology this compact volume provides authoritative state-of-the-art primer level overviews of the various Cancer types, their evaluation and treatment. Every aspect of oncology is ......
Fatigue. Chronic pain. Insomnia. Depression. These are just a few of the ongoing, debilitating symptoms that plague some breast-cancer survivors long after their treatments have officially ended. This title is filled with portraits of more than seventy women who are living with the aftermath of breast cancer.
Dr. Suzanne M. Miller demonstrates her approach to counseling women with breast cancer. The goal of her cognitive-social approach is to help women with the many challenges associated with treatment for breast cancer.
While the first healers were musicians who relied on rhythm and song to help cure the sick, over time Western thinkers and doctors lost touch with these traditions. In the West, for almost two millennia, the roles of the healer and the musician have been strictly separated. Until recently, that is. Over the past few decades there has been a ......
One of the goals of the fourth edition of this series is the presentation of new molecular findings which add to our understanding of tumour pathogenesis and may additionally be useful diagnostically. Such information is particularly relevant to the study of bone tumours and tumour-like lesions and, in this volume, the authors have included an ......
Psychological Approaches for Helping Patients and Families
Offers a base of information about genetics, explanations of what is and is not known about cancer genetics, and descriptions of the genetic counseling process. But most importantly, this volume extensively reviews the psychological problems and dilemmas that patients concerned about hereditary cancer experience.
Current Therapy and Guidelines from the Children's Oncology Group
Three of every four children and adolescents with cancer can now be cured. However, physicians are using increasingly intensive treatment regimens. These treatments can expose patients to toxic chemotherapeutic agents, invasive surgical procedures, and radiation oncology interventions that risk disfigurement, neuropsychiatric damage, and ......
