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The Deadly Rise of Anti-science

A Scientist's Warning
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Dr. Peter Hotez discusses how the antivaccine movement became a dangerous political campaign promoted by elected officials and amplified by news media, causing thousands of American deaths.

Shortlisted for the Non-Obvious Book Awards by the Non-Obvious Company

During the height of the COVID-19 pandemic, one renowned scientist, in his famous bowtie, appeared daily on major news networks such as MSNBC, NPR, the BBC, and others. Dr. Peter J. Hotez often went without sleep, working around the clock to develop a nonprofit COVID-19 vaccine and to keep the public informed. During that time, he was one of the most trusted voices on the pandemic and was even nominated for a Nobel Peace Prize for his selfless work. He also became one of the main targets of anti-science rhetoric that gained traction through conservative news media.

In this eyewitness story of how the anti-vaccine movement grew into a dangerous and prominent anti-science element in American politics, Hotez describes the devastating impacts it has had on Americans health and lives. As a scientist who has endured antagonism from anti-vaxxers and been at the forefront of both essential scientific discovery and advocacy, Hotez is uniquely qualified to tell this story. By weaving his personal experiences together with information on how the anti-vaccine movement became a tool of far-right political figures around the world, Hotez opens readers eyes to the dangers of anti-science. He explains how anti-science became a major societal and lethal force: in the first years of the pandemic, more than 200,000 unvaccinated Americans needlessly died despite the widespread availability of COVID-19 vaccines. Even as he paints a picture of the world under a shadow of aggressive ignorance, Hotez demonstrates his innate optimism, offering solutions for how to combat science denial and save lives in the process.

Peter J. Hotez, MD, PhD (HOUSTON, TX), is a professor of pediatrics and molecular virology and microbiology and the founding dean of the National School of Tropical Medicine at Baylor College of Medicine, where he is also the codirector of the Texas Childrens Center for Vaccine Development. He is the author of Preventing the Next Pandemic: Vaccine Diplomacy in a Time of Anti-science and Vaccines Did Not Cause Rachels Autism: My Journey as a Vaccine Scientist, Pediatrician, and Autism Dad.

Preface Chapter 1. An Army of Patriots Turns against the Scientists Chapter 2. Health Freedom Propaganda in America Chapter 3. Red COVID Chapter 4. An Anti-science Political Ecosystem Chapter 5. A Tough Time to Be a Scientist Chapter 6. The Authoritarian Playbook Chapter 7. The Hardest Science Communication Ever Chapter 8. Southern Poverty Law Center for Scientists Literature Cited Index

Dr. Peter Hotez discusses how the antivaccine movement became a dangerous political campaign promoted by elected officials and amplified by news media, causing thousands of American deaths.

The authors short, passionate polemic, dense with studies and charts, provides overwhelming evidence that scientific research benefits humanity and that vaccines are lifesavers. Supremely well-informed.

— Kirkus Reviews

Virologist and vaccine expert Peter Hotez has provided the definitive work on this era....[His] warning about the broader implications of COVID denial must be heeded.

— Arthur Caplan, Science

Harrowing and deeply alarming. [Hotezs] analysis of the modern US anti-vaccine movement and its entanglement with the authoritarian right is astute.

— New Scientist

[A] powerful eyewitness account of anti-scientific activities in the USA.

— Naomi Oreskes, The Lancet

[Hotez] demonstrates that anti-science aggression is one of many threats humanity and our collective civilisation is facing.

— The Lancet Infectious Diseases

See All Reviews

A professor of pediatrics and molecular virology at Baylor and a courageously outspoken advocate for public health, Hotez documents how agitators on the extreme right have graduated from trying to sow mistrust in science to targeting individual scientists such as himself. The heart of his book is a call for government agencies and professional organizations to wage an aggressive battle against anti-vaccination and anti-science propaganda.

— Michael Hiltzik, Los Angeles Times

[Dr. Hotez is] better known as a 2022 Nobel Peace Prize nominee for helping to develop two COVID-19 vaccines that were administered more than 100 million times in India and Indonesia. Last year, he wrote a new book, The Deadly Rise of Anti-science: A Scientists Warning. For his pains, he has been villainized by the antivaccine community online and labeled by antivaxxer presidential candidate Robert F. Kennedy Jr. as the OG, or Original Gangster.

— TIME (TIME100 Health 2024)

Hotez paints a bleak picture of public science denial during the pandemic, embedded in historic context....[He] makes the case that the denial of scientific knowledge is not isolated, random, or benign. Rather, it is an organized and dangerous movement. Along with offering context for anti-science movements, he humanizes the scientists working to help us.

— Health Affairs

Hotez is well-positioned to raise alarms about anti-science. He is a physician scientist who, for both personal and professional reasons, was publicly defending vaccines long before COVID-19...The Deadly Rise of Anti-Science foretells a worrisome future for vaccines in America.

— Philip Eil, The Nation

Dr. Peter Hotez sheds light on the pervasive anti-vaccine lobby that has gained significant traction....Reversing the damage caused by anti-vaccine movements requires addressing the underlying psychological and political factors that fuel this skepticism.

— Express Healthcare Management

We need an infrastructure to assist scientists in their desperately needed ancillary role as science communicators. Peter Hotez...offers direction to achieving these new goals. We hope that scientific institutions will take heed and follow.

— Genetic Literacy Project

Hotez, who has extensive experience with coronaviruses, describes anti-science efforts regarding vaccinations in general, vaccination of children, and COVID-19 vaccinations in particular. It is time for scientists and the public to resist these attacks....Recommended.

— Choice

In this era when truth, evidence and science are, to put it bluntly, under attack, it is important that we share lessons and provide support in our health services and policy research community....[Dr. Hotez] advocates for organized supports from scientific organizations and associations to equip and protect scientists who are working to defend science.

— Maggie Keresteci, CAHSPR

Because government health agencies have been ineffective in opposing hateHotez argues that more is needed to protect biomedical scientists.

— APS Forum on Physics & Society

Chronicles much of the anti-vaccination movement, the promotion of misinformation, and the role of politics in the spread of anti-science, all the while detailing the deliberate attacks and aggressions on scientists. Though it establishes anti-sciences historical roots in authoritarianism, the focus of this book is on the politics and climate of the current state of science.

— Eugene N. Anderson, PhD (University of California, Riverside), © Doodys Review Service, 2024

A short, frightening analysis of the rise of anti-science sentiment in the United States and throughout the world....Hotez is particularly well-suited to provide such analysis and warning.

— Reformed Journal

Globally, anti-science is a key part of the far-right, autocratic, populist playbook. Hotezs terrifying but profoundly important book shows how deep the anti-science rabbit hole goes, who is thriving on chaos, and why anti-science is surging everywhere. The book is an eye-opening exposé of the catastrophic consequences of anti-science.

— Madhukar Pai, MD, PhD, Professor of Epidemiology and Global Health, McGill University

Dr. Hotez is the pioneer of a new breed: physician-scientist-warrior. He led the efforts in the United States against mis- and dis-information during the COVID pandemic and, long before that, took on the anti-science and anti-vax movements. His story, remarkable work, and insights are aptly portrayed in The Deadly Rise of Anti-science.

— Eric Topol, MD, Professor and Executive Vice President, Scripps Research Institute

Peter Hotez, a physician scientist fighting the war on infectious diseases, describes the impact of the anti-science movement. The victims are those who fall prey to its rhetoric and suffer the consequences. This is a must-read for anyone interested in the state of scientific affairs and public health.

— Daniel Salmon, Institute for Vaccine Safety, Johns Hopkins University Bloomberg School of Public Health

Vaccines are a critical public health tool in preventing life-threatening illness and death. Their use and lifesaving impact are now seriously threatened by the deadly rise of anti-science. Hotez provides a front-row seat to the unfolding infectious disease catastrophe we are facing. He delivers a clarion call to action like no one else can.

— Michael T. Osterholm, Regent Professor and Director, Center for Infectious Disease Research and Policy, University of Minnesota

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